Method for determining properties of red blood cells
AssigneeSandia Corporation
InventorPaul L. Gourley
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Abstract
A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.
Claims9
A method for determining hemoglobin comprising:
- determining the wavelength of a longitudinal mode of a laser microcavity containing only a liquid;
- determining the wavelength of a transverse mode of said longitudinal mode of the laser microcavity containing a red blood cell in the liquid;
- determining hemoglobin concentration as a direct function of the difference between the wavelength of the longitudinal mode and the transverse mode.
Dependencies are inferred from the claim text.