Stabilized pharmaceutical preparation
AssigneeTakeda Chemical Industries, Ltd.
InventorsMakoto Fukuta, Hiroki Itoh
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Abstract
A stabilized pharmaceutical preparation which is coated with a coating agent comprising an agent for the protection from light, said agent being capable of producing free radicals when exposed to ultraviolet rays, and a free radical scavenger; which is stable to light, especially ultraviolet rays, or heat, and which has excellent storage-stability.
Claims19
A stabilized pharmaceutical preparation comprising a tablet coated with a coating agent wherein the coating agent comprises (i) a component for the protection from light present in an amount capable of protecting the pharmaceutical from light, said component being capable of producing free radicals when exposed to ultraviolet rays, and (ii) a free radical scavenger present in an amount capable of scavenging free radicals.
A stabilized pharmaceutical preparation comprising a tablet coated with a coating agent wherein the coating agent comprises (i) titanium oxide present in an amount capable of protecting the pharmaceutical from light and (ii) sodium hydrogensulfite, ascorbic acid, sodium ascorbate, calcium ascorbate, dl-α-tocopherol or dl-α-tocopherol acetate.
A stabilized pharmaceutical preparation comprising a tablet coated with a coating agent wherein the coating agent comprises (i) an oily substance selected from the group consisting of an ester and an alcohol, and (ii) a free radical scavenger present in an amount capable of scavenging free radicals.
A stabilized pharmaceutical preparation comprising a tablet coated with a coating agent wherein the coating agent comprises (i) an oily substance selected from the group consisting of an ester and an alcohol, and (ii) a basic substance.
A method of stabilizing a pharmaceutical preparation comprising coating a tablet with a coating agent wherein said coating agent comprises (i) a component for the protection from light present in an amount capable of protecting the pharmaceutical from light, said component being capable of producing free radicals when exposed to ultraviolet rays, and (ii) a free radical scavenger present in an amount capable of scavenging free radicals.
A method of stabilizing a pharmaceutical preparation comprising coating a tablet with a coating agent wherein said coating agent comprises (i) an oily substance selected from the group consisting of an ester and an alcohol, and (ii) a free radical scavenger present in an amount capable of scavenging free radicals.
A method of stabilizing a tablet comprising coating a pharmaceutical preparation with a coating agent wherein said coating agent comprises (i) an oily substance selected from the group consisting of an ester and an alcohol, and (ii) a basic substance.
Dependencies are inferred from the claim text.