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AssigneesThe Board of Regents of the University of Oklahoma, Janssen Pharmaceutica NV
InventorsLoyd V. Allen, Bingnan Wang, John Desmond Davies
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A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
A rapidly dissolving pharmaceutical dosage form, comprising:
A rapidly dissolving pharmaceutical dosage form, comprising:
A rapidly dissolving pharmaceutical dosage form, comprising:
Dependencies are inferred from the claim text.