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US 6,187,336 B1Granted
Process for producing a solid which is rapidly soluble in the oral cavity
AssigneeNikken Chemicals Co., Ltd.
InventorsMutsuo Okumura, Sachio Motegi, Tadashi Ukigaya, Katsuaki Miyazaki
Life of this patent
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Abstract
A rapidly soluble solid in the oral cavity comprising erythritol, which has a porous structure; and a process for producing a rapidly soluble solid in the oral cavity comprising erythritol, which comprises the steps of: preparing a composition comprising erythritol and appropriate moisture, kneading the composition, molding the kneaded composition, and drying the molded composition under reduced pressure.
Claims25
A process for producing a solid which is rapidly soluble in the oral cavity, wherein the solid has a porous structure, which process comprises the steps of:
- preparing a composition consisting essentially of 80 to 99.9% by weight of erythritol, a component selected from the group consisting of a drug, a pharmaceutically acceptable additive, a food, and a food additive, and moisture in an amount of 5 to 20% by weight based on the solid content of the composition, wherein said pharmaceutically acceptable additive is selected from the group consisting of sucrose, lactose, xylitol, D-mannitol, maltitol, lactitol, magnesium stearate, calcium stearate, talc, light silicic acid anhydride, silicon dioxide hydrate and a surfactant,
- kneading the composition,
- molding the composition, and
- drying the molded composition under reduced pressure.
1 more element
Dependencies are inferred from the claim text.