Acidic buffered nasal spray
AssigneeWisconsin Alumni Research Foundation
InventorsJames E. Gern, Anne G. Mosser
Life of this patent
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Abstract
Disclosed herein are buffered flowable nasal sprays having a pH of between 4.0 and 5.0. They are primarily water and a citrate (or citrate/phosphate) buffer. They may also contain sodium chloride, thickeners, and/or preservatives. The preparations are able to maintain the aforesaid pH under conditions simulating a runny nose. Methods of using these preparations to inhibit the spread of rhinovirus and/or diseases caused by rhinovirus are also disclosed.
Claims10
A method of killing rhinovirus virus in a human nose comprising spraying a preparation into the nose, wherein preparation comprises:
- a buffered flowable nasal preparation having a pH of between 4.0 and 5.0, comprising water, and a citrate, wherein the preparation is sufficiently buffered so as to be able to maintain a pH below 6.0 when challenged under the “Buffering Power” test.
A method of inhibiting the spread of rhinoviral infection comprising spraying a preparation into a human's nose, wherein preparation comprises:
- a buffered flowable nasal preparation having a pH of between 4.0 and 5.0, comprising water, and a citrate, wherein the preparation is sufficiently buffered so as to be able to maintain a pH below 6.0 when challenged under the “Buffering Power” test.
Dependencies are inferred from the claim text.