Process and a device for the production of a flat administration form comprising a preparation which contains pharmaceutical active substances
AssigneeLTS Lohmann Therapie-Systeme AG
InventorsThomas Hille, Ludwig Grader, Klaus Schumann
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process and a device for the production of a flat administration form comprising a preparation that contains pharmaceutical active substances. The flowable preparation is conveyed to an applicator unit (12) by means of a metering pump, and flows through a distribution chamber (2) having a distribution plate (3) provided with passages (4). This application device (12) transfers the preparation onto a layer of the flat administration form (6,11) which is therefor contacted with the distribution plate (3) for a short time.
Claims24
A device for the production of flat dermal or transdermal therapeutic administration forms for pharmaceutically active substances comprising:
- a) an application unit (12) equipped with a distribution chamber (2) for flowable preparations having a distribution plate (3) provided with at least one passage (4),
- b) a counter-pressure plate (8, 9), and
- c) a precise proportioning pump.
In a process for the production of flat dermal or transdermal therapeutic administration forms having a drug acceptor layer containing an accurate dose of a drug preparation containing a pharmaceutically active substance, the improvement of said process comprising
- (a) conveying said accurate dose of the drug preparation, which is flowable at least during processing, by means of precise proportioning pump into a distribution chamber (2) of an applicator unit (12), equipped with a distribution plate (3) having at least one passage (4), and
- (b) transferring said accurate dose of the drug preparation through said distribution plate (3) onto a defined area of said acceptor layer (7) of the flat administration form by short term contacting the outer surface of said distribution plate (3) with said defined area of said acceptor layer.
Dependencies are inferred from the claim text.