Avian E. coli Iss polypeptide
AssigneeNorth Dakota State University
InventorsLisa K. Nolan, Shelley M. Horne, Michael Robinson
Life of this patent
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Abstract
A nucleic acid sequence encoding an avian E. coli iss gene and an Iss polypeptide encoded thereby are disclosed. Methods for detecting and using such sequences are also provided as are immunogenic compositions and vaccines.
Claims20
An isolated and purified avian E. coli Iss polypeptide.
A diagnostic kit for detecting the presence of antibodies in a biological sample that specifically bind to an avian E. coli Iss polypeptide which comprises a packaging, containing, separately packaged:
- (a) a solid phase capable of having attached thereto a polypeptide;
- and
- (b) a known amount of a purified Iss polypeptide that specifically reacts with antibodies specific for the polypeptide.
A method for detecting antibodies that bind to an avian E. coli Iss polypeptide in a biological sample comprising the steps of:
- a) contacting an amount of a purified Iss polypeptide with the biological sample suspected of containing avian E. coli Iss antibodies under conditions that allow for formation of an antibody-antigen complex;
- and
- b) detecting the antibody-antigen complex.
Dependencies are inferred from the claim text.