Back to results
US 6,187,047 B1Granted
Bone grafting matrix
AssigneeOrquest, Inc.
InventorsMichael K. Kwan, Stephen D. Pacetti, Ronald K. Yamamoto
Life of this patent
Estimating the term…
Abstract
A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less.
Claims8
A method of making a biodegradable porous bone grafting matrix which maintains physical integrity for a period of at least about 3 days after implant and its porosity for about 7-14 days after implant into a physiological environments in which bone replacement is occurring, comprising the steps of:
- (a) forming a dispersion comprising a biodegradable water-insoluble biopolymer, a water-soluble binder, and particulate calcium phosphate mineral immobilized by said binder or biopolymer;
- (b) forming said dispersion into a porous matrix;
- (c) cross-linking said porous matrix.
Dependencies are inferred from the claim text.