2-amino-1,3-alkanediol compositions for inducing/stimulating hair growth and/or retarding hair loss
AssigneeSociete L'Oreal S.A.
InventorsDominique Fagot, Olivier Gaillard, Michel Philippe, Bruno Bernard
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Abstract
Topically applicable hair growth-/hair loss-affecting cosmetic/pharmaceutical compositions for treating mammalian subjects with hair or scalp disorders, comprise an effective amount of at least one 2-amino-1,3-alkanediol compound having the structural formula (I): formulated into a physiologically topically acceptable carrier medium therefor.
Claims21
A method for inducing or stimulating hair growth and/or retarding hair loss on a mammalian subject in need of said treatment comprising topically applying to the hair and/or skin an effective amount of a cosmetic or pharmaceutical composition of matter, comprising a hair growth stimulating and/or hair loss retarding effective amount of at least one 2-amino-1,3-alkanediol compound having the structural formula (I) which compound induces hair growth and/or retards hair loss:
- in which R1 is a saturated, and optionally is a hydroxylated, linear or branched hydrocarbon radical having from 4 to 28 carbon atoms;
- R2 is a hydrogen atom or the radical:
- wherein R3 is a saturated or unsaturated, optionally hydroxylated, linear or branched hydrocarbon radical having from 1 to 29 carbon atoms, wherein the hydroxyl group thereof is optionally esterified by a saturated or unsaturated, linear or branched acyl radical having from 2 to 30 carbon atoms;
- and X is a hydrogen atom or the OH radical, or at least one optical isomer or diastereoisomer thereof, in a physiologically topically acceptable carrier medium therefor.
The method as defined by claim 19, wherein said disorder or affliction is an alopecia induced by chemotherapeutic anticancer therapy.
A method for inducing or stimulalting hair growth and/or retarding hair loss on a mammalian subject in need of said treatment comprising topically applying an effective amount of a cosmetic or pharamaceutical composition of matter, consisting essentially of a hair growth stimulating and/or hair loss retarding effective amount of at least one 2-amino-1,3-alkanediol compound having the structural formula (I) which compound induces hair growth and/or retards hair loss:
- in which R1 is a saturated, optionally hydroxylated, linear or brached hydrocarbon radical having from 4 to 28 carbon atoms;
- R2 is a hydrogen atom or the radical:
- wherein R3 is a saturated or unsaturated, optionally hydroxylated, linear or branched hydrocarbon radical having from 1 to 29 carbon atoms, wherein the hydroxyl group thereof is optionally esterified by a saturated or unsaturated, linear or branched acyl radical having from 2 to 30 carbon atoms;
- and X is a hydrogen atom or is an OH radical, or at least one optical isomer or diastereoisomer thereof, in a physicologically topically acceptable carrier medicum therefor.
Dependencies are inferred from the claim text.