Inhibition of cytokine production by polymethoxylated flavones
AssigneesThe United States of America as represented by the Secretary of Agriculture, Amgen Inc.
InventorsJohn A. Manthey, Carl L. Manthey, Antonio Montanari
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Abstract
A method of inhibiting the production of cytokines, particularly inhibiting the production of tumor necrosis factorα, interleukin-10, and macrophage inflammatory protein-1α and the like, in a mammal, including a human, in need thereof which involves administering to such mammal an effective amount, preferably cytokine production inhibiting amount, of a polymethoxylated flavone.
Claims14
A method of inhibiting the production of cytokines, comprising administering to a mammal in need of such treatment an effective, cytokine production inhibiting amount of a polymethoxylated flavone.
A method of reducing the in vivo amount of cytokines in a mammal, comprising administering to said mammal an effective amount of a polymethoxylated flavone.
Dependencies are inferred from the claim text.