N-hydroxyurea derivative and pharmaceutical composition containing the same

An N-hydroxyurea derivative having the formula (I):

• herein in the formula (I), R3 represents A, either one of R1, R2, and R4 represents a 3-pyridyl group or 3-pyridyl lower alkyl group, the remaining groups of R1, R2 and R4 independently represent a hydrogen atom, a halogen atom, or a substituted or unsubstituted C1 to C5 alkyl group, where the substituent represents a carboxyl group, a methoxycarbonyl group, or an ethoxycarbonyl group, R5 represents a hydrogen atom, a methyl group, or an ethyl group, R6 represents a hydrogen atom, a methyl grout, an ethyl group, or C3 to C6 cycloalkyl group, and B represents a bond, a C1 to C5 alkylene group, or a C2 and C5 alkenylene group, or B—C(R5)represents a C2 to C4 alkylene group having a benzene ring in the middle thereof.

An N-hydroxyurea derivative having the formula (I):

• wherein in the formula (I), R4 represents A, either one of R1, R2, and R3 represents a 3-pyridyl group or 3-pyridyl lower alkyl group, the remaining groups of R1, R2, and R3 independently represent a hydrogen atom, a halogen atom, or a substituted or unsubstituted C1 to C5 alkyl group, where the substituent represents a carboxyl group, a methoxycarbonyl group, or an ethoxycarbonyl group, R5 represents a hydrogen atom, a methyl group, or an ethyl group, R6 represents a hydrogen atom, a methyl group, an ethyl group, or C3 to C5 cycloalkyl group, and B represents a bond, a C1 to C5 alkylene group, a C2 to C5 alkenylene group, or a C2 to C5 alkynylene group.