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US 6,184,034 B2Granted
Deoxyribonuclease II proteins and cDNAS
AssigneeTrustees of Dartmouth College
InventorsAlan Eastman, Ronald Krieser
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Abstract
The present invention provides cDNAs encoding deoxyribonuclease II and isolated, purified deoxyribonuclease II proteins. Antibodies against this protein and antisense agents targeted to a cDNA or corresponding mRNA encoding deoxyribonuclease II are provided. In addition, methods of identifying and using modulators of deoxyribonuclease II activity and apoptosis are described.
Claims5
A cDNA encoding a deoxyribonuclease II enzyme, said cDNA comprising SEQ ID NO:
- 1 or 2.
Dependencies are inferred from the claim text.