Buccal delivery system
AssigneeNovartis Consumer Health S.A.
InventorKimon Ventouras
Life of this patent
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Abstract
A controlled release lozenge having pleasant organoleptic properties, said lozenge consisting essentially of (a) a soluble filler which is selected from the group consisting of maltitol, xylitol, sorbitol, mannitol, lactose, dextrose, saccharose, fructose, and mixtures thereof; (b) an insoluble film forming agent which is capable of forming an insoluble matrix, said insoluble film forming agent is selected from the group consisting of a polyacrylate, ethyl cellulose, polyvinylchloride, cellulose acetate, cellulose acetate phthalate, and shellac; (c) a swellable polymer which is selected from the group consisting of xanthan gum, guar gum, alginic acid or a salt thereof, pectin, polyvinyl alcohol, polysaccharide, and cellulose derivatives; and (d) at least one active substance.
Claims7
A controlled release lozenge having pleasant organoleptic properties, said lozenge consisting essentially of
- (a) 50 to 99 weight percent, based on the total weight of the lozenge, of a soluble filler which is selected from the group consisting of maltitol, xylitol, sorbitol, mannitol, lactose, dextrose, saccharose, fructose, and mixtures thereof;
- (b) 0.5 to 30 weight percent, based on the total weight of the lozenge, of an insoluble film forming agent which is capable of forming an insoluble matrix, said insoluble film forming agent is selected from the group consisting of a polyacrylate, ethyl cellulose, polyvinylchloride, cellulose acetate, cellulose acetate phthalate, shellac, and mixtures thereof;
- (c) 0.5 to 30 weight percent, based on the total weight of the lozenge, of a swellable polymer which is selected from the group consisting of xanthan gum, guar gum, alginic acid or a salt thereof, pectin, polyvinyl alcohol, polysaccharide, cellulose derivatives, and mixtures thereof;
- and
- (d) at least one active substance.
A controlled release lozenge having pleasant organoleptic properties, said lozenge consisting essentially of
- (a) 55 to 95 weight percent, based on the total weight of the lozenge, of a soluble filler which is selected from the group consisting of maltitol, xylitol, sorbitol, mannitol, lactose, dextrose, saccharose, fructose, and mixtures thereof;
- (b) 0.5 to 24 weight percent, based on the total weight of the lozenge, of an insoluble film forming agent which is capable of forming an insoluble matrix, said insoluble film forming agent is selected from the group consisting of a polyacrylate, ethyl cellulose, polyvinylchloride, cellulose acetate, cellulose acetate phthalate, shellac, and mixtures thereof;
- (c) 0.5 to 24 weight percent, based on the total weight of the lozenge, of a swellable polymer which is selected from the group consisting of xanthan gum, guar gum, alginic acid or a salt thereof, pectin, polyvinyl alcohol, polysaccharide, and cellulose derivatives;
- and
- (d) at least one active substance.
Dependencies are inferred from the claim text.