Methods for prevention and/or treatment of thrombocytopenia
AssigneeDynaGen, Inc.
InventorsNicolae Istrate, Gita Muni, Edgard Brauner, Fazal Raheman
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Abstract
The present invention is directed to a method of treating subjects exhibiting thrombocytopenia or at risk of developing thrombocytopenia. The method includes the step of administering to the subject exhibiting thrombocytopenia or at risk of developing thrombocytopenia, an effective amount of a Pseudomonas solvent extract or active fraction thereof. The Pseudomonas solvent extract is administered in an amount effective to increase platelet levels in the subject.
Claims21
A method for treating a subject having thrombocytopenia comprising:
- subcutaneously administering to a subject in need of such treatment a Pseudomonas acetone extract or an active fraction thereof, in an amount effective to increase platelet counts in the subject.
A method of treating thrombocytopenia, comprising:
- administering to a subject in need of such treatment a Pseudomonas acetone extract or active fraction thereof, wherein the Pseudomonas acetone extract is obtainable by incubating acetone with a Pseudomonal culture to produce a first precipitate;
- mixing the first precipitate with ethanol and collecting the ethanol extract and precipitating an active material from the ethanol extract by acetone precipitation to produce the Pseudomonas acetone extract, and wherein the Pseudomonas acetone extract is administered in an amount effective to increase platelet counts in the subject.
A method of treating a subject at risk of developing thrombocytopenia comprising:
- subcutaneously administering to a subject at risk of developing thrombocytopenia a Pseudomonas acetone extract or an active fraction thereof that increases circulating platelet counts in an amount effective to prevent platelet counts in the subject from decreasing below 50,000 platelets per microliter.
Dependencies are inferred from the claim text.