Small peptides with antipathogenic activity, treated plants and methods for treating same
AssigneesUSDA/ARS Southern Regional Research Center, Auburn University
InventorsAnne-Laure Moyne, Thomas E. Cleveland, Sadik Tuzun
Life of this patent
Estimating the term…
Abstract
The invention relates to two lipopeptides a1 and a2 produced by Bacillus subtilis and their use as an anitfungal agent against Aspergillus flavus. Both peptides are cyclic, acidic and have broad range of antifungal and antimicrobial activity. Both peptides belong to the Bacillomycin D family. A method and composition for controlling aflatoxin contamination in plants susceptible to alflatoxin-producing fungi, like Aspergillus flavus or Aspergillus parasiticus is also disclosed.
Claims29
An isolated antifungal Bacillus subtilis PTA-1767 peptide selected from the group consisting of a1 and a2, and having antifungal activity against Aspergillus flavus, wherein said peptide is a cyclic peptide comprising a β-amino fatty acid.
A biologically pure culture of Bacillus subtilis identified as strain PTA-1767.
A method for controlling aflatoxin contamination in plants susceptible to aflatoxin-producing fungi comprising treating a plant with peptides a1 and/or a2 from Bacillus subtilis PTA-1767.
A composition effective to control Aspergillus flavus which comprises in a mixture, an acceptable carrier and at least one active component selected from the group consisting of B. subtilis PTA-1767 and extracts thereof wherein said active component comprises at least one of peptides a1 and a2.
Dependencies are inferred from the claim text.