Method for improved bonding of prosthetic devices to bone
AssigneeSulzer Orthopedics Inc.
InventorsBrian D. Burkinshaw, Jack R. Frautschi
Life of this patent
Estimating the term…
Abstract
The surface molecules of a modified polymeric prosthetic device participate in the free radical polymerization reaction of a bone cement such as polymethylmethacrylate, thereby providing improved bonding between the prosthesis and the bone to which it is attached.
Claims13
A method for providing improved bonding between a polymeric prosthetic device and bone comprising:
- producing a surface modified prosthetic device by reacting the surface of a prosthetic device with a surface modifying agent which comprises a first reactive group and a second reactive group under conditions effective to cause covalent bonding between the first reactive group and the surface molecules of the polymeric prosthetic device;
- and
- contacting the surface modified prosthetic device with bone in the presence of PMMA under conditions effective to cause covalent bonding between the second reactive group on the surface modified prosthetic device and the PMMA, wherein the second reactive group is capable of participating in the polymerization reaction of PMMA.
A surface modified polymeric prosthetic device capable of improved bonding to PMMA wherein surface molecules of the prosthetic device are covalently bonded to the first reactive group of a surface modifying agent which comprises a first reactive group and a second reactive group, wherein the second reactive group is capable of participating in the polymerization reaction of PMMA.
A method for providing improved bonding between a polymeric prosthetic device and bone comprising:
- producing a surface modified prosthetic device by reacting the surface of a prosthetic device with a surface modifying agent which comprises a first reactive group selected from the group consisting of azide, diazo, aliphatic azo, diazirine, ketene, ketone, and peroxy groups, and a second reactive group under conditions effective to cause covalent bonding between the first reactive group and the surface molecules of the polymeric prosthetic device;
- and
- contacting the surface modified prosthetic device with bone in the presence of PMMA under conditions effective to cause covalent bonding between the second reactive group on the surface modified prosthetic device and the PMMA.
Dependencies are inferred from the claim text.