Bladder submucosa seeded with cells for tissue reconstruction
AssigneeChildren's Medical Center Corporation
InventorAnthony Atala
Life of this patent
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Abstract
Methods and materials for tissue reconstruction, repair, and/or augmentation are disclosed. The invention provides isolated bladder submucosa seeded with cells for use in tissue reconstruction. The methods of the invention include the use of isolated bladder submucosa seeded with cells for augmentation of bladder and other organs and tissues.
Claims12
A method for surgically augmenting a tissue of a subject, the method comprising augmenting the tissue of the subject with isolated bladder submucosa seeded with cells, wherein said submucosa is obtained by microdissection of bladder tissue.
A method for repairing a damaged tissue, the method comprising contacting the damaged tissue with isolated bladder submucosa seeded with cells, under conditions such that growth of the tissue occurs, such that the damaged tissue is repaired, wherein said submucosa is obtained by microdissection of bladder tissue.
A material for tissue reconstruction or augmentation, the material comprising isolated bladder submucosa seeded with cells, wherein said submucosa is obtained by microdissection of bladder tissue.
A method for preparing isolated bladder submucosa seeded with cells, the method comprising the steps of:
- obtaining isolated bladder submucosa by microdissection of bladder tissue;
- and
- seeding the isolated bladder submucosa with cells.
Dependencies are inferred from the claim text.