Method and apparatus for detecting a condition associated with acute cardiac ischemia

A device for detecting and reporting a condition associated with acute cardiac ischemia in a patient, comprising:

• (a) a plurality of electrodes for sensing patient ECG signals;
• (b) a processing unit in communication with the plurality of electrodes the processing unit configured to:
• (i) derive heartbeat data from the patient's ECG data;
• (ii) form a vector of heartbeat data from the derived heartbeat data;
• (iii) produce a set of global features by projecting the vector of heartbeat data onto one or more predetermined basis vectors that define an acute cardiac ischemic ECG subspace or a non-ischemic ECG subspace;
• and
• (iv) classify the set of global features to determine whether the global features are indicative of an acute cardiac ischemic condition;
• and
• (c) a user output in communication with the processing unit for reporting whether the acute cardiac ischemic condition is determined to be present.

A method of detecting and reporting a condition associated with acute cardiac ischemia in a patient, comprising:

• (a) obtaining one or more leads of ECG data from the patient;
• (b) deriving heartbeat data from the patient's ECG data;
• (c) forming a vector of heartbeat data from the derived heartbeat data;
• (d) generating a local classification statistic by:
• (i) deriving a set of local features from the patient;
• and
• (ii) classifying the set of local features to produce the local classification statistic;
• (e) generating a global classification statistic by:
• (i) producing a set of global features by projecting the vector of heartbeat data onto one or more basis vectors that define an acute cardiac ischemic ECG subspace or a non-ischemic ECG subspace;
• and
• (ii) classifying the set of global features to produce the global classification statistic;
• (f) classifying the local classification statistic and the global classification statistic to determine whether the local and global classification statistics are indicative of an acute cardiac ischemic condition;
• and
• (g) reporting whether the acute cardiac ischemic condition is determined to be present.

A method of detecting and reporting a condition associated with acute cardiac ischemia in a patient, comprising:

• (a) obtaining one or more leads of ECG data from the patient;
• (b) deriving heartbeat data from the patient's ECG data;
• (c) forming a vector of heartbeat data from the derived heartbeat data;
• (d) deriving a set of local features from the patient;
• (e) producing a set of global features by projecting the vector of heartbeat data onto one or more basis vectors that define an acute cardiac ischemic ECG subspace or a non-ischemic ECG subspace;
• (f) jointly classifying the set of global features and the set of local features to determine whether the global features and local features are indicative of an acute cardiac ischemic condition;
• and
• (g) reporting whether the acute cardiac ischemic condition is determined to be present.

A device for detecting and reporting a condition associated with acute cardiac ischemia in a patient, comprising:

• (a) electrodes adapted to be placed on the patient to sense ECG signals;
• (b) a user input;
• (b) a processing unit in communication with the user input and the electrodes, wherein the processing unit is configured to acquire ECG data from the ECG signals and determine the presence of an acute cardiac ischemic condition by:
• (i) analyzing the ECG data;
• (ii) calculating a classification statistic reflective of a cardiac condition based on at least one characteristic obtained from the ECG data;
• and
• (iii) comparing the classification statistic with a threshold that reflects a desired sensitivity/specificity operating point for the device, wherein the sensitivity/specificity operating point of the device is adapted to be selected by a user of the device via the user input;
• wherein the threshold used by the processing unit is automatically adjusted for higher specificity after the processing unit determines the presence of the acute cardiac ischemic condition in the patient.

A device for detecting and reporting a condition associated with acute cardiac ischemia in a patient, comprising:

• (a) electrodes adapted to be placed on the patient to sense ECG signals;
• (b) a processing unit in communication with the electrodes, wherein the processing unit is configured to acquire ECG data from the ECG signals and determine the presence of an acute cardiac ischemic condition by:
• (i) forming a vector of heartbeat data from the ECG data;
• (ii) projecting the vector of heartbeat data onto one or more predetermined basis vectors defining an acute cardiac ischemic ECG subspace or a non-ischemic ECG subspace to produce one or more global features;
• (iii) calculating a classification statistic reflective of a cardiac condition based on the one or more global features;
• and
• (iv) comparing the classification statistic with a threshold that reflects a desired sensitivity/specificity operating point for the device.