Method of inactivation of viral and bacterial blood contaminants
AssigneeBaxter International Inc.
InventorsSang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
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Abstract
Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
Claims5
A photosensitizer capable of binding viral, bacterial, or parasitic contaminants in a biological solution, and further capable of inactivating said viral, bacterial or parasitic contaminant upon irradiation without substantially impairing said biological solution, comprised of:
- a) an intercalating psoralen chemical backbone structure;
- b) at least one halogen atom;
- and
- c) at least one non-hydrogen bonding ionic moiety.
A fluorescent photosensitizer capable of binding viral, bacterial, or parasitic contaminants in a biological solution, and fuirther capable of inactivating said viral, bacterial or parasitic contaminants upon irradiation without substantially impairing said biological solution, comprised of:
- a) an intercalating psoralen chemical backbone structure;
- and
- b) at least one halogen atom.
Dependencies are inferred from the claim text.