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US 6,165,990 AGranted
Antisense polynucleotide
AssigneeBoard of Regents, The University of Texas System
InventorsPomila Singh, Thomas G. Wood
Life of this patent
Estimating the term…
Abstract
The present invention discloses methods for the treatment of colon cancer. The expression of gastrin by colon cancers is inhibited by the use of antisense gastrin expression. Methods are disclosed for the preparation of expression constructs and the use of such constructs to inhibit colon cancer growth.
Claims8
An isolated genetic construct comprising an antisense polynucleotide sequence of SEQ ID NO:13 flanked by SEQ ID NO:
- 3 at the 5' end, and by SEQ ID NO:4 at the 3' end.
A pharmaceutical composition comprising an isolated genetic construct comprising an antisense polynucleotide sequence of SEQ ID NO:13 flanked by SEQ ID NO:
- 3 at the 5' end, and by SEQ ID NO:4 at the 3' end and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.