Back to results
US 6,165,515 AGranted
Method for treatment of osteoporosis
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsToshikatsu Matsuyama, Jin-emon Konishi
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsToshikatsu Matsuyama, Jin-emon Konishi
Estimating the term…
A therapeutic agent for osteoporosis brought about by a decrease in estrogen comprises an extract from inflammatory rabbit skin inoculated with vaccinia virus as an effective component. In ovariectomized rats, a model animal for osteoporosis brought about by a decrease in estrogen, the extract from inflammatory rabbit skin inoculated with vaccinia virus has an excellent action for maintaining bone volume and bone strength. The therapeutic agent containing the extract as an active component is very useful for treatment and prevention of osteoporosis brought about by a decrease in estrogen which is frequently caused by menopause or ovariectomy in women. The extract from inflammatory rabbit skin inoculated with vaccinia virus has a high safety profile even when administered for a long term.
A method for treatment of osteoporosis caused by or accompanying a decrease in estrogen in a patient in need of such treatment comprising administering to said patient a pharmaceutically effective amount of an extract from inflammatory tissue inoculated with vaccinia virus, wherein said extract is a protein free hygroscopic powder, has an ultraviolet adsorption max of 255-275 nm, and is positive for ninhydrin reaction.
A method for maintaining or increasing bone volume, bone quality, or bone strength in a patient afflicted with osteoporosis caused by or accompanying a decrease in estrogen comprising administering to said patient in need thereof a pharmaceutically effective amount of an extract from inflammatory tissue inoculated with vaccinia virus, wherein said extract is a protein free hygroscopic powder, has an ultraviolet adsorption max of 255-275 nm, and is positive for ninhydrin reaction.
A method for inhibiting a decrease in trabecular connectivity and for inhibiting an increase in trabecular unconnectivity in a patient afflicted with osteoporosis caused by or accompanying a decrease in estrogen comprising administering to said patient a pharmaceutically effective amount of an extract from inflammatory tissue inoculated with vaccinia virus, wherein said extract is a protein free hygroscopic powder, has an ultraviolet adsorption max of 255-275 nm, and is positive for ninhydrin reaction.
Dependencies are inferred from the claim text.