Polysaccharide derivative/magnetic metal oxide composite
AssigneeMeito Sangyo Kabushiki Kaisha
InventorsShigeo Maruno, Masakatsu Hasegawa, Takamasa Hanaichi, Katsutoshi Murase, Hisato Yamada, Hideo Nagae, Kyoji Kito
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Abstract
The present invention provides a polysaccharide-magnetic metal oxide complex consisting of a polysaccharide derivative obtained by carboxyalkyl-etherifying and unsubstituted or substituted aminoalkyl-etherifying a polysaccharide (the above carboxy group and/or amino group may be of a salt form) and a magnetic metal oxide. The above complex has a slow blood clearance and a low toxicity and is useful as a nuclear magnetic resonance imaging contrast medium.
Claims21
A complex of a magnetic metal oxide and a polysaccharide derivative, wherein the derivative is obtained by carboxyalkyl-etherifying and aminoalkyl-etherifying a polysaccharide, where the aminoalkyl is optionally substituted.
Dependencies are inferred from the claim text.