Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor
AssigneeBaylor College of Medicine
InventorRabih O. Darouiche
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AssigneeBaylor College of Medicine
InventorRabih O. Darouiche
Estimating the term…
A medical device of metallic or non-metallic material coated with a combination of antiseptics and a method for coating such an implant with a combination of antiseptics is provided. Different combinations of antiseptics can be used for different types of medical devices depending on the spectrum of organisms that cause the infections related to each device. The combination of different antiseptics has a synergistic effect against certain bacteria and fungi. The combination of antiseptic can be applied to the surface of a metallic device by dissolving the combination of antiseptics and a polymeric sticking agent in an acid solution to form an antiseptic solution, and applying the antiseptic solution, in an effective concentration to inhibit the growth of bacterial and fungal organisms, to at least a portion of the surfaces of the medical device. The antiseptic combination can be applied to the surface of and impregnate the material of a non-metallic implant by forming an antiseptic composition by dissolving the combination of antiseptics in an organic solvent and adding a penetrating agent to the composition, and applying the antiseptic composition to at least a portion of the medical implant under conditions where the antiseptic composition permeates the material of the medical implant.
A method for impregnating non-metallic medical device with a combination of antiseptics comprising the steps of:
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