US 6,160,010 AGranted

BTK inhibitors and methods for their identification and use

AssigneeParker Hughes Institute

InventorsFatih M. Uckun, Yaguo Zheng, Sutapa Ghosh

Life of this patent

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Abstract

The invention provides BTK inhibitors, methods for their identification and use, and pharmaceutical compositions comprising BTK inhibitors.

Claims6

Dependent claims

A method for increasing sensitivity of cancer cells to chemotherapy, comprising administering to a subject undergoing chemotherapy with a chemotherapeutic agent a BTK inhibitor in an amount sufficient to increase the sensitivity of cancer cells to the chemotherapeutic agent.

Dependencies are inferred from the claim text.

Facts

Application: 09/358,521Filed 22 Jul 1999 · continuation
Priority: 19 Mar 1999
Granted: 12 Dec 2000
Term ends: Not estimatedThe source records don’t support an estimate.

Classification7 codes

A61K 31/225
Of acyclic acids, e.g. pravastatin: polycarboxylic acids
A61K 31/275
Medicinal preparations containing organic active ingredients: nitriles; Isonitriles
A61K 31/277
Nitriles; Isonitriles: having a ring, e.g. verapamil
A61K 31/40
Having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins: having five-membered rings with one nitrogen as the only ring hetero atom,…

Family

Serial273,191Parent of this continuation · filed 19 Mar 1999
US 6,160,010 AThis patent

From the US filing history. Foreign family members aren’t listed.

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