Use of glycosaminoglycans degrading enzymes for management of airway associated diseases
AssigneeInsight Strategy & Marketing Ltd.
InventorOron Yacoby-Zeevi
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Abstract
A method of managing a patient having an accumulation of mucoid, mucopurulent or purulent material containing glycosaminoglycans, the method comprising the step of administering at least one glycosaminoglycans degrading enzyme to the patient in an amount therapeutically effective to reduce at least one of the following: the visco-elasticity of the material, pathogens infectivity and inflammation. An article of manufacture comprising an inhaler including, as an active ingredient, at least one glycosaminoglycans degrading enzyme for generating aerosols including the enzyme for management a patient having an accumulation of mucoid, mucopurulent or purulent material containing glycosaminoglycans.
Claims13
A method of reducing, in a patient, the visco-elasticity of mucoid, mucopurulent or purulent material containing glycosaminoglycans, the method comprising the step of administering to the patient at least one glycosaminoglycans degrading enzyme selected from the group consisting of heparanase and heparinase in an amount therapeutically effective to reduce the visco-elasticity of the material.
Dependencies are inferred from the claim text.