Nucleic acids encoding tospovirus genome and expression thereof
AssigneeNovartis Finance Corporation
InventorsRobert Willem Goldbach, Dirk Peters, Johannes Jacobus Ludgerus Gielen, Petrus Theodorus de Haan, Arnoldus Johannes Kool, Martinus Quirinus Joseph Marie van Grinsven
Life of this patent
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Abstract
Recombinant DNA constructs comprising a DNA coding for transcription into an RNA sequence of tospoviruses or into RNA sequences related thereto, the use of such DNA constructs to transform plants having reduced susceptibility to tospovirus infection and probes for the isolation of tospovirus or diagnosis of plant tospovirus diseases.
Claims16
Recombinant DNA constructs comprising a DNA sequence under expression control of a promoter and a terminator functioning in plants, which DNA sequence encodes an RNA sequence selected from the group consisting of:
- (a) the S RNA nucleotide sequence from 1 to 2915 depicted in FIG. 4;
- (b) the S RNA nucleotide sequence from 2763 to 1987 depicted in FIG. 4;
- (c) the L RNA nucleotide sequence depicted in FIG. 6B;
- (d) an RNA nucleotide sequence, encoding for a tospovirus protein, in which one or more codons of the RNA sequence of (a), (b) or (c) have been replaced by codons coding for the same amino acid or termination signal;
- and
- (e) an RNA sequence complementary to the RNA sequence of (a) (b), (c) or (d).
Dependencies are inferred from the claim text.