Phenoxyethylamine derivatives, method of preparation application as medicine and pharmaceutical compositions containing same
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques
InventorsDennis Bigg, Marie-Odile Galcera
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Abstract
Novel method for treating warm-blooded animals for inducing anti-emetic activity, accelerating gastric emptying, modifying intestinal transit and anxiety, depression and sleep disorders by administration of a compound of the formula ##STR1## wherein Ar is unsubstituted or substituted phenyl, R is alkyl of 1 to 10 carbon atoms or cycloalkyl of 3 to 10 carbon atoms and its acid addition salts.
Claims5
A method of inducing anti-emetic activity in warm-blooded animals comprising administering to warm-blooded animals an anti-emetically effective amount of a compound selected from the group consisting of a compound of the formula ##STR11## wherein Ar is unsubstituted or substituted phenyl, R is alkyl of 1 to 10 carbon atoms or cycloalkyl of 3 to 10 carbon atoms and its acid addition salts.
A method of accelerating gastric emptying in warm-blooded animals comprising administering to warm-blooded animals an amount sufficient to accelerate gastric emptying of a compound selected from the group consisting of a compound of the formula ##STR12## wherein Ar is unsubstituted or substituted phenyl, R is alkyl of 1 to 10 carbon atoms or cycloalkyl of 3 to 10 carbon atoms and its acid addition salts.
A method of modifying intestinal transit in warm-blooded animals comprising administering to warm-blooded animals an amount sufficient to modify intestinal transit of a compound of the formula ##STR13## wherein Ar is unsubstituted or substituted phenyl, R is alkyl of 1 to 10 carbon atoms or cycloalkyl of 3 to 10 carbon atoms and its acid addition salts.
A method of treating anxiety, depression and sleep disorders in warm-blooded animals comprising administering to warm-blooded animals an amount sufficient to treat said conditions of a compound of the formula ##STR14## wherein Ar is unsubstituted or substituted phenyl, R is alkyl of 1 to 10 carbon atoms or cycloalkyl of 3 to 10 carbon atoms and its acid addition salts.
Dependencies are inferred from the claim text.