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AssigneesMonell Chemical Senses Center, Takasago International Corporation, Sheseido Co., Ltd.
InventorsDiego Restrepo, George Gomez, Gary K. Beauchamp, Masahiro Tanida, Tsutomu Saito, Shoji Nakamura, Yoshirou Okazaki, Shinichi Wachi, Yasuhiro Takashima
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Adjuvants for preventing adaptation to odors comprising one or compounds having the following formula (1): ##STR1## wherein R1 is a C1 to C8 lower alkyl group or a C7 to C9 aralkyl group, and R2 is a hydrogen atom or a C1 to C8 lower alkyl group, are described, as are compositions containing the same, and methods for preventing the adaptation to odors. Methods for increasing intracellular calcium ion levels and for prolonging the sensory response of chemoreceptive cells also described.
A method for preventing adaptation to an odor-emitting substance in a subject, said method comprising combining an effective amount of an adjuvant comprising one or more compounds of the following formula (1):
Dependencies are inferred from the claim text.