Tart cherry compounds that have antioxidant activity and uses thereof
AssigneeBoard of Trustees operating Michigan State University
InventorsMuraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray
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Abstract
Compounds that are isolatable from cherries and have antioxidant activity, and methods for isolating these compounds are described. In particular, the invention relates to 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol and 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,5-diol, which have antioxidant activity. These antioxidant compounds and compositions containing these compounds are useful as food preservatives, dietary supplements, nutraceuticals, and phytoceuticals.
Claims25
An isolated compound or a mixture of isomers of the formula:
- ##STR5## wherein R.sub.1 and R.sub.2 are selected from the group consisting of a hydroxyl and a hydrogen and one of R.sub.1 and R.sub.2 is hydroxyl.
Isolated 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol.
Isolated 1-(3',4'-dihydroxylcinnamoyl)-cyclopenta-2,5-diol.
A composition which comprises:
- (a) one or more isolated compounds of the formula:
- ##STR6## wherein R.sub.1 and R.sub.2 are selected from the group consisting of a hydroxyl or a hydrogen and one of R.sub.1 and R.sub.2 is the hydroxyl;
- and
- (b) a non-toxic carrier for the compound.
A composition which comprises:
- (a) isolated compound 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol or as a mixture with an isolated 1-(3',4'-dihydroxylcinnamoyl)-cyclopenta-2,5-diol,;
- and
- (b) a non-toxic carrier for the compound.
A composition which comprises:
- (a) isolated compound 1- (3',4'-dihydroxylcinnamoyl)-cyclopenta-2,5-diol or as a mixture with isolated compound 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol,;
- and
- (b) a non-toxic carrier for the compound.
A method for inhibiting oxidation of an oxidizable material which comprises:
- introducing with the material one or more isolated compounds of the formula:
- ##STR7## wherein R.sub.1 and R.sub.2 are selected from the group consisting of a hydroxyl and a hydrogen, and one of the R.sub.1 and R.sub.2 is the hydroxyl, in an amount, so that oxidation of the material is inhibited.
A method of inhibiting oxidation of an oxidizable material which comprises:
- introducing with the material the isolated compound 1- (3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol, in an amount, so that oxidation of the material is inhibited.
A method of inhibiting oxidation of a material which comprises:
- introducing with the material a mixture of compound 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,5-diol, in an amount, so that oxidation of the material is inhibited.
A method of inhibiting oxidation of an oxidizable material which comprises:
- introducing with the material the isolated mixture of 1- (3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol 1-(3',4'-dihydroxycinnamoyl) -cyclopenta 2,5-diol, in an amount, so that oxidation of the material is inhibited.
Dependencies are inferred from the claim text.