1,2-dithiolane compounds

A compound selected from those of the formula (I):

• ##STR16## wherein:
• Ra represents linear or branched (C.sub.1 -C.sub.8)alkylene,
• Rb represents a single bond, or linear or branched (C.sub.1 -C.sub.6)alkylene,
• Z represents:
• thiocarbamate ##STR17## wherein the oxygen is bonded to Ra, and R.sub.1 represents a group selected from hydrogen, linear or branched (C.sub.1 -C.sub.6)alkyl, aryl, and aryl-(C.sub.1 -C.sub.6)alkyl in which alkyl is linear or branched, or
• the thioamide ##STR18## wherein thiocarbonyl is bonded to Ra, and R.sub.1 is as defined hereinbefore,
• T represents a group ##STR19## wherein R.sub.2 and R.sub.3, which may be identical or different, each independently of the other represents a group selected from hydrogen, linear or branched (C.sub.1 -C.sub.6)alkyl, cycloalkyl, cycloalkyl-(C.sub.1 -C.sub.6) alkyl in which alkyl is linear or branched, heterocycloalkyl, heterocycloalkyl-(C.sub.1 -C.sub.6)alkyl in which alkyl is linear or branched, aryl, aryl-(C.sub.1 -C.sub.6)alkyl in which alkyl is linear or branched, heteroaryl, heteroaryl-(C.sub.1 C.sub.6)alkyl in which alkyl is linear or branched, and amino-(C.sub.1 -C.sub.6)alkyl in which alkyl is linear or branched (amino being optionally substituted by one or two identical or different groups selected from linear or branched (C.sub.1 -C.sub.6)alkyl, aryl, and aryl-(C.sub.1 -C.sub.6)alkyl in which alkyl is linear or branched),
• its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, it being understood that:
• "cycloalkyl" means a mono- or bi-cyclic, saturated or unsaturated group having 3 to 8 carbon atoms, each of those groups being optionally substituted by one or more identical or different groups selected from halogen, hydroxy, linear or branched (C.sub.1 -C.sub.6)alkyl, linear or branched (C.sub.1 -C.sub.6)alkoxy, and amino (amino itself optionally substituted by one or two, identical or different linear or branched (C.sub.1 -C.sub.6)alkyl),
• "heterocycloalkyl" means cycloalkyl in which one or two carbon atoms have been replaced by a heteroatom selected, identically or differently, from nitrogen, oxygen, and sulphur,
• "aryl" means phenyl, naphthyl, indenyl, tetrahydronaphthyl, dihydronaphthyl, or indanyl, each of those groups being optionally substituted by one or more, identical or different, groups selected from halogen, linear or branched (C.sub.1 -C.sub.6)alkyl, hydroxy, linear or branched (C.sub.1 -C.sub.6)alkoxy, amino, mono- or di-(C.sub.1 -C.sub.6)alkyl-amino in which alkyl moiety is linear or branched, carboxy, and linear or branched (C.sub.1 -C.sub.6)alkoxycarbonyl,
• "heteroaryl" means aryl in which one or two carbon atoms have been replaced by a heteroatom selected, identically or differently, from oxygen, nitrogen, and sulphur.