Potassium channel agonists
AssigneeMerck & Co., Inc.
InventorsJoseph J. Salata, Jixin Wang, Michael C. Sanguinetti, Nancy K. Jurkiewicz
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Abstract
This application discloses a method of treating cardiac ventricular arrhythmias and repolarization abnormalities associated with long QT syndrome and/or congestive heart failure comprising the adminstration of an agonist of the slowly activating cardiac delayed rectifier potassium current (I.sub.Ks).
Claims12
A method of treating cardiac ventricular arrhythmias and repolarization abnormalities associated with long QT syndrome and/or congestive heart failure comprising the adminstration of a therapeutically effective amount of an agonist of the slowly activating cardiac delayed rectifier potassium current (I.sub.Ks) to a patient in need of such treatment.
A method for improving contractile dysfunction in a congestive heart failure patient comprising the adminstration of a therapeutically effective amount of an agonist of the slowly activating cardiac delayed rectifier potassium current (I.sub.Ks) to a patient in need of such treatment.
Dependencies are inferred from the claim text.