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US 6,150,325 AGranted
Bicyclic tachykinins antagonists, preparation thereof and their use in pharmaceutical compositions
AssigneeA. Menarini Industrie Farmaceutiche Riunite S.r.l.
InventorsFederico Arcamone, Carlo Alberto Maggi, Laura Quartara, Danilo Giannotti
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Abstract
This invention relates to novel compounds of general formula (I): ##STR1## and to pharmaceutical compositions containing them.
Claims14
Bicycl compounds of general Formula ##STR5## wherein X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5 and X.sub.6, same or different from one another, represent a --NR'CO-- or a --CONR'-- group, where R' is H or C.sub.1-3 alkyl;
- Y represents a group selected from --NRCO--, --CONR-- or --SS--
- wherein R is H or C.sub.1-3 alkyl;
- at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 groups, same or different from one another, is hydrophilic and the remaining groups are hydrophobic;
- m and n, same or different from one another, are each an integer number from 1 to 4.
1 more element
Dependencies are inferred from the claim text.