Process for production of L-aspartic acid
AssigneeNippon Shokubai Co., Ltd.
InventorsMasaharu Mukouyama, Satomi Komatsuzaki
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Abstract
A process for producing crystalline L-aspartic acid is disclosed essentially consisting of the steps of preparing a mix solution containing fumaric acid, ammonia and an alkaline metal hydroxide, reacting the mix solution with aspartase to give a reaction solution containing L-aspartate and crystallizing L-aspartic acid out of the reaction solution, wherein a further amount of ammonia is added to the reaction solution containing L-aspartate and subsequently fumaric acid is added thereto to crystallize L-aspartic acid. The process can provide crystalline L-aspartic acid of high purity in a good workability without the need of any complicated steps.
Claims12
A process for producing crystalline L-aspartic acid comprising
- preparing a mix solution comprising fumaric acid, ammonia and an alkaline metal hydroxide,
- reacting the mix solution with aspartase to give a reaction solution containing L-aspartate and crystallizing L-aspartic acid out of the reaction solution, wherein a further amount of ammonia is added to the reaction solution containing L-aspartate and subsequently fumaric acid is added thereto to crystallize L-aspartic acid.
A process for producing crystalline L-aspartic acid comprising:
- preparing a mix solution comprising fumaric acid, ammonium L-aspartate, ammonia and an alkaline metal hydroxide,
- reacting the mix solution with aspartase to give a reaction solution containing L-aspartate and crystallizing L-aspartic acid out of the reaction solution, wherein a further amount of ammonia is added to the reaction solution containing L-aspartate and subsequently fumaric acid is added thereto to crystallize L-aspartic acid.
A process for producing crystalline L-aspartic acid comprising:
- preparing a mix solution comprising fumaric acid, ammonia and an alkaline metal hydroxide,
- reacting the mix solution with aspartase to give a reaction solution containing L-aspartate and crystallizing L-aspartic acid out of the reaction solution, wherein a further amount of ammonia is added to the reaction solution containing L-aspartate, the reaction solution is heated, fumaric acid is added to the reaction solution, and the reaction solution is cooled to crystallize L-aspartic acid.
A process for producing crystalline L-aspartic acid comprising:
- preparing a mix solution comprising fumaric acid, ammonium L-aspartate, ammonia and an alkaline metal hydroxide,
- reacting the mix solution with aspartase to give a reaction solution containing L-aspartate and crystallizing L-aspartic acid out of the reaction solution, wherein a further amount of ammonia is added to the reaction solution containing L-aspartate, the reaction solution is heated, fumaric acid is added thereto to the reaction solution, and the reaction solution is cooled to crystallize L-aspartic acid.
Dependencies are inferred from the claim text.