Molecular markers for the diagnosis of human diseases including Crohn's disease

A method for the diagnosis of Crohn's disease in a patient;

• which comprises the step of;
• a) subjecting a nucleic acid sequence obtained from a biological sample of said patient to at least one of the following to determine the presence of Crohn's disease marker:
• i) hybridization of said nucleic acid sequence with a specific probe for the diagnosis of Crohn's disease said probe comprising a nucleic acid sequence as set forth in SEQ ID NO:2, or a fragment thereof having a minimum of 100 bp in length, for a time sufficient for hybridization of said to occur;
• and detection of hybridization of said nucleic acid sequence with said probe;
• or
• ii) amplification by RAP-PCR of said nucleic acid sequence of said biological sample using a specific PCR primer as set forth in SEQ ID NO:1 for the diagnosis of Crohn's disease, and detection of an amplified nucleic acid sequence,
• wherein detection of hybridization in step i) or detection of an amplified nucleic acid sequence in step ii) is indicative of Crohn's disease marker.