Back to results
US 6,149,641 AGranted
Local delivery of estrogen for angiogenesis
AssigneeSciMed Life Systems, Inc.
InventorMark T. Ungs
Life of this patent
Estimating the term…
Abstract
A method for inducing angiogenesis in blood vessels proximal to ischemic tissue or proximal to stenosed regions including application of an estrogen compound to the blood vessel walls at a treatment site proximal to or upstream of the stenosis. A preferred delivery device is a double walled drug delivery catheter having porous outer walls. Another suitable delivery device is a drug injection device for injecting angiogenic material into blood vessel walls. One delivery method utilizes iontophoresis.
Claims11
A method of increasing blood flow to ischemic tissue, comprising the steps of:
- advancing a delivery device to a vascular site proximal of ischemic tissue;
- and
- applying an estrogen compound to the vascular site proximal of the ischemic tissue with resulting induction of angiogenesis at the vascular site.
Dependencies are inferred from the claim text.