Noninvasive apparatus and method for the determination of cardiac valve function
OwnerWalter S. Seitz, Steven P. Olseninventors
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Abstract
A method and device for determining a plurality of cardiovascular parameters are described, wherein the parameters are determined from noninvasively obtained data, thereby obviating the need for invasive procedures such as cardiac catheterization. These determinations are enabled by incorporating fluid dynamics and thermodynamics equations with nonivasively obtained mechanical cardiac event data to estimate a desired cardiovascular parameter. Exemplary parameters obtainable with the method and device include aortic and mitral valve areas, cardiac left ventricular stroke volume, and aortic and mitral valve pressure gradients.
Claims44
A noninvasive method for measuring an area of a cardiac valve of a patient comprising the steps of:
- noninvasively measuring a plurality of mechanical cardiac parameters of the patient, including a heart rate, a stroke volume, and a time period between an empty state and a filled state of a cardiac chamber;
- and
- calculating a cardiac valve area with the use of the measured cardiac parameters.
A device for noninvasively measuring an area of a cardiac valve of a patient comprising:
- means for noninvasively measuring a plurality of mechanical cardiac parameters of the patient, including a heart rate, a stroke volume, and a time period between an empty state and a filled state of a cardiac chamber;
- and
- means for calculating a cardiac valve area with the use of the measured cardiac parameters.
A noninvasive method for measuring a cardiac left ventricular stroke volume of a patient comprising the steps of:
- collecting a cardiac echocardiogram from a patient;
- noninvasively measuring an end-diastolic dimension and an end-systolic dimension of a left ventricle from the echocardiogram;
- and
- calculating the stroke volume from the end-diastolic dimension and the end-systolic dimension.
A device for noninvasively measuring a cardiac left ventricular stroke volume of a patient comprising the steps of:
- means for collecting a cardiac echocardiogram from a patient;
- means for noninvasively measuring an end-diastolic dimension and an end-systolic dimension of a left ventricle from the echocardiogram;
- and
- means for calculating the stroke volume from the end-diastolic dimension and the end-systolic dimension.
A noninvasive method for calculating a mitral valve pressure gradient of a patient, comprising the steps of:
- noninvasively measuring a heart rate of the patient;
- noninvasively measuring a left ventricular diastolic filling period of the patient;
- and
- calculating the mitral valve pressure gradient from the heart rate and the diastolic filling period.
A device for noninvasively determining a mitral valve pressure gradient of a patient, comprising the steps of:
- means for noninvasively measuring a heart rate of the patient;
- means for noninvasively measuring a left ventricular diastolic filling period of the patient;
- and
- means for calculating the mitral valve pressure gradient from the heart rate and the diastolic filling period.
A noninvasive method of measuring an aortic valve pressure gradient of a patient comprising the steps of:
- noninvasively measuring a left ventricular wall thickness of the patient;
- noninvasively measuring a left ventricular end-diastolic dimension of the patient;
- and
- calculating the aortic valve pressure gradient from the measured wall thickness and the end-diastolic dimension.
A device for noninvasively measuring an aortic valve pressure gradient of a patient comprising:
- means for noninvasively measuring a left ventricular wall thickness of the patient;
- means for noninvasively measuring a left ventricular end-diastolic dimension of the patient;
- and
- means for calculating the aortic valve pressure gradient from the measured wall thickness and the end-diastolic dimension.
Dependencies are inferred from the claim text.