Method for producing chlorins and bacteriochlorins containing polyether
AssigneeDeutsches Krebsforschungszentrum Stiftung des Offentlichen
InventorsHannsjorg Sinn, Hans-Hermann Schrenk, Michael Kaus, Wolfgang Maier-Borst, Gerd Stehle
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Abstract
This invention relates to a process for the preparation of polyether-including chlorins and/or bacteriochlorins, comprising the following steps: (a) bonding a polyether to a porphyrin and (b) reacting the polyether-including porphyrin with a reducing agent. Furthermore, this invention concerns the polyether-including chlorins and bacteriochlorins, obtained by the process, as well as the use thereof for the photodynamic treatment of tumors.
Claims12
A process for the preparation of polyether-including chlorins and/or bacteriochlorins, comprising the following steps:
- (a) bonding a polyether to a porphyrin and
- (b) reacting the polyether-including porphyrin with a reducing agent.
A polyether-including chlorin or bacteriochlorin, of the formula:
- ##STR1##
A method of photodynamic therapy, comprising the use of a polyether-including chlorin or bacteriochlorin, formed by a process comprising the steps of:
- (a) bonding a polyether to a porphyrin and
- (b) reacting the polyether-including porphyrin with a reducing agent.
A method of photodynamic therapy, comprising the use of a polyether-including chlorin or bacteriochlorin, of the formula:
- ##STR2##
Dependencies are inferred from the claim text.