Biphenyl compounds and use thereof as oestrogenic agents

A compound of the formula ##STR14## wherein X is ##STR15## R.sub.1 and R.sub.2 are individually hydrogen or alkyl of 1 to 4 carbon atoms, R.sub.3 is selected from the group consisting of hydrogen, halogen and alkyl and alkoxy of 1 to 4 carbon atoms, R.sub.4 is in the meta or para position and is selected from the group consisting of hydrogen, halogen, --OH, alkyl and alkenyl and alkynyl of up to 4 carbon atoms, alkoxy and alkylthio of 1 to 4 carbon atoms, optionally ##STR16## R.sub.A and R.sub.B are individually hydrogen or alkyl of 1 to 4 carbon atoms, or taken together with the nitrogen form a saturated 5 to 6 member ring heterocycle with an optional second heterocycle selected from the group consisting of oxygen, nitrogen and sulfur, n is an integer from 2 to 7, R.sub.5 is hydrogen or halogen, R.sub.6 and R.sub.7 are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 4 carbon atoms and phenyl optionally substituted in the meta or para position with R.sub.4 and their addition salts with non-toxic, pharmaceutically acceptable bases and acids, with the provisos that X is not (A), when R.sub.1, R.sub.2, and R.sub.3 are hydrogen and R.sub.4 is --OH and X is not (B) when R.sub.5 and R.sub.6 and R.sub.7 are hydrogen or when R.sub.5 and R.sub.6 are hydrogen and R.sub.7 is alkyl of 1 to 4 carbon atoms.