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US 6,147,115 AGranted
Antitumor compositions and methods of treatment
AssigneeEli Lilly and Company
InventorsThomas A. Crowell, J. Jeffry Howbert, John S. Ward
Life of this patent
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Abstract
This invention provides certain sulfonamide compounds, formulations, and a method for treating susceptible neoplasms in mammals using certain sulfonamide compounds.
Claims9
A compound useful in the treatment of susceptible neoplasms in mammals having the formula ##STR7## wherein X.sup.1 is halo;
- X.sup.2 is hydrogen, halo, or CF.sub.3 ;
- and
- wherein
- B is:
- a) C.sub.2 -C.sub.7 alkyl with the proviso that when B is n-butyl X.sup.2 is other than hydrogen;
- e) a C.sub.5 -C.sub.6 cycloalkyl;
- or
- f) RZR.sup.1 -where R is phenyl or C.sub.1 -C.sub.2 alkyl, R.sup.1 is CH.sub.2 or C.sub.2 H.sub.4, and Z is oxygen or sulfur;
- or pharmaceutically acceptable salts thereof.
6 more elements
Dependencies are inferred from the claim text.