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US 6,147,112 AGranted
Use of 2,5-dihydroxybenzenesulfonic derivatives for the normalization of endothelial function
AssigneeLaboratorios Del Dr. Esteve, S.A.
InventorJose Esteve-Soler
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Abstract
Method for the use of 2,5,-dihydroxybenzenesulphonic derivatives for normalizing endothelial function and treating sexual dysfunctions, the vascular complications of diabetes and vascualr disorders of endothelial origin are disclosed. Preferred 2,5-dihydroxybenzenesulponic derivatives are calcium dobesilate, ethamsylate and persilate.
Claims5
A method of treating sexual dysfunction, vascular complications of diabetes or vascular disorders of endothelial origin comprising administering to a patent in need of such treatment an effective amount of a 2,5-dihydroxybenzenesulfonic compound of general formula I:
- ##STR2## in which R represents H or SO.sub.3 --;
- B represents Ca++ or H.sub.2 N(C.sub.2 H.sub.5).sub.2 ;
- n represents 1 or 2;
- and
- m represents 1 or 2.
2 more elements
Dependencies are inferred from the claim text.