Clonidine preparations
AssigneeCuratek Pharmaceuticals Holding, Inc.
InventorRobert J. Borgman
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Abstract
Sympathetically maintained peripheral neuropathic pain syndromes are relieved by topically applying, to the affected region of a patient suffering from such pain, a pain relieving amount of an aqueous gel comprising clonidine, a water-gelling amount of a pharmaceutically acceptable gelling agent and having a physiologically tolerable pH value. Pain relief was achieved with applied amounts of clonidine in the range of about 2 milligrams per day to about 6 mg per day.
Claims25
A topical aqueous gel suitable for relieving sympathetically maintained peripheral neuropathic pain syndrome and comprising clonidine, water, and a water-gelling amount of a pharmaceutically acceptable gelling agent selected from the group consisting of carbomers, glycerine polyacrylate, and mixtures thereof, the topical aqueous gel having a physiologically tolerable pH value.
A method for relieving sympathetically maintained peripheral neuropathic pain syndromes which comprises applying topically to the affected region of a patient suffering from such pain a pain relieving amount of an aqueous gel comprising clonidine, and a water-gelling amount of a pharmaceutically acceptable gelling agent selected from the group consisting of carbomers, glycerine polyacrylate, and mixtures thereof, the topical aqueous gel having a physiologically tolerable pH value.
Dependencies are inferred from the claim text.