Methods for treating gastroesophageal reflux disease
AssigneeSepracor Inc.
InventorsJohn R. McCullough, Thomas P. Jerussi
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Abstract
Methods utilizing the optically pure (+) isomer of norcisapride are disclosed. This compound has surprisingly been found to be a potent drug for the treatment of disorders caused by gastrointestinal motility dysfunction. Finally, the (+) isomer of norcisapride also avoids certain adverse side effects and certain adverse drug interactions.
Claims19
A method of treating or preventing a disorder caused by gastrointestinal motility dysfunction in a human which comprises administering to said human a therapeutically effective amount of (+) norcisapride, or a pharmaceutically acceptable salt thereof, substantially free of its (-) stereoisomer.
A method of eliciting a prokinetic effect in a human to treat gastro-esophageal reflux disease in said human which comprises administering to said human a therapeutically effective amount of (+) norcisapride, or a pharmaceutically acceptable salt thereof, substantially free of its (-) stereoisomer.
Dependencies are inferred from the claim text.