Use of antimineralocorticoid compounds against drug withdrawal syndrome

A method of treating narcotic withdrawal symptoms and narcotic dependence symptoms in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of an antimineral corticoid compound of the formula ##STR22## wherein X.sub.b is selected from the group consisting of --OH, acetyloxy, propionyloxy, methoxy and ethoxy Y.sub.b is selected from the group consisting of --CH.sub.2 --CH.sub.2 --CO.sub.2 M, --CH.sub.2 --CH.sub.2 --SO.sub.2 M and --CH.sub.2 --CH.sub.2 --CH.sub.2 --OH, M is selected from the group consisting of hydrogen, alkali metal and --NH.sub.4, R.sub.2b is alkyl, alkenyl and alkynyl of up to 8 carbon atoms, R.sub.3b is hydrogen, R.sub.4b is alkyl of 1 to 8 carbon atoms and R.sub.5b is hydrogen and the dotted lines are a possible second bond and their salts with pharmaceutically acceptable acids and bases sufficient to treat narcotic withdrawal symptoms and narcotic dependence symptoms.