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US 6,147,049 AGranted
Tetra-hydronaphthalenes
AssigneeGivaudan Roure (International) SA
InventorsPeter Gygax, Hans-Ulrich Gonzenbach
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Abstract
The present invention provides compounds of formula I: ##STR1## wherein R.sup.1 is hydrogen or methyl and R.sup.2 is alkyl. These compounds are useful as fixatives in fragrance compositions. Processes of making such compounds are also provided.
Claims18
A compound of formula I:
- ##STR12## wherein R.sup.1 is hydrogen or methyl and R.sup.2 is alkyl.
A process for preparing a compound of formula I:
- ##STR13## wherein R.sup.1 is hydrogen or methyl and R.sup.2 is alkyl comprising:
- (a) reacting a compound of formula II:
- ##STR14## with a compound of formula III:
- ##STR15## wherein Hal is halogen;
- (b) acylating a tetrahydronaphthalene of formula IV:
- ##STR16## produced by the reaction in (a) to form a compound of formula V:
- ##STR17## (c) reacting the compound of formula V with an alcohol or a glycol to form a ketal of formula VI:
- ##STR18## wherein R' is an alkyl residue or R'--R' is a divalent alkyl residue that forms a dioxolane ring;
- and
- (d) reacting a compound of formula VI with magnesium and a formamide of formula VIII:
- ##STR19## to form a compound of formula I, wherein R.sup.3 and R.sup.4 are two organic residues or together form a ring.
8 more elements
A fragrance composition comprising a fragrance and a fixative, wherein the fixative is a compound of formula I:
- ##STR20## wherein R.sup.1 is hydrogen or methyl and R.sup.2 is alkyl.
Dependencies are inferred from the claim text.