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US 6,146,885 AGranted
Cell-type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins
AssigneeUniversity of Medicine and Dentistry of New Jersey
InventorRalph C. Dornburg
Life of this patent
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Abstract
The present invention pertains to retroviral vector particles having target cell specificity which comprise a retroviral vector having an antigen binding site of an antibody fused to the envelope protein of the retroviral vector, wherein the antigen binding site of the antibody replaces the natural viral receptor binding site.
Claims2
A plasmid identified in FIG. 2c as pTC4.
A plasmid identified in FIG. 2d as pTC5.
Dependencies are inferred from the claim text.