Pharmaceutical preparation and a method for the treatment of diabetes
AssigneeDiataranz Limited
InventorRobert Bartlet Elliott
Life of this patent
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Abstract
A method of treatment of humans suffering from diabetes which involves transplantation into the human of viable porcine islets capable of producing insulin within its host. The invention also includes the particular preparation for such transplantation and its method of preparation which involves extraction from a piglet at near full term gestation (whether delivered prematurely or not) and treatment of the tissue with nicotinamide and/or any compound exhibiting similar growth promoting and cytoprotective effects and the subsequent administration of such a compound or compounds to the patient after the transplantation.
Claims14
A method for treatment of a mammalian patient suffering from diabetes which comprises:
- (a) extracting neonatal piglet islet cells;
- (b) treating said islets with nicotinamide;
- (c) injecting so as to transplant into said mammalian patient and effective amount of viable piglet islet cells which have been treated in accordance with step (b), said viable islets being capable of producing insulin in a host;
- (d) administering nicotinamide to said mammalian patient at least subsequent to transplantation;
- and
- (e) administering a casein-free diet to said mammalian patient.
A preparation comprising:
- an effective amount of viable islets extracted from a neonatal piglet delivered within 4 weeks after birth, said islets being capable of producing insulin in a host and been treated during preparative procedures with nicotinamide, said islets being in an injectable form for transplantation into a mammalian patient.
Dependencies are inferred from the claim text.