US 6,144,199 A · Method for imaging vessel wall anatomy and strain

Abstract

A method for depicting the anatomy and quantitative tissue strain of a biological tissue. A spatially resolved, double quantum filtered, nuclear magnetic resonance frequency spectrum is acquired from either .sup.1 H or .sup.2 H nuclei in the tissue. Values in the time domain or frequency domain representations of the free induction decay signal are mapped in 2 spatial dimensions so as to selectively depict histological layers of the tissue anatomy. The residual quadrupolar or dipolar splitting is calculated from the free induction decay signal, and then correlated with a tissue strain value by utilizing a known formula describing the correlation between residual quadrupolar or dipolar splitting and tissue strain. The tissue strain value is then mapped in two spatial dimensions.

Claims14

Dependent claims

A method for depicting strain in a wall of a hollow viscus, comprising

(a) acquiring a spatially resolved, double quantum filtered, nuclear magnetic resonance frequency spectrum from water molecules in the wall of the hollow viscus
(b) calculating a derived quantity describing a magnetic resonance parameter for said spectrum, said derived quantity being based on a parameter selected from the group consisting of a distribution of residual quadrupolar splitting and a distribution of residual dipolar splitting
(c) correlating said derived quantity with a value selected from the group consisting of a strain-to-quadrupolar-splitting value and a strain-to-dipolar-splitting value, and
(d) displaying said value as a graphic in at least two spatial dimensions.

1 more element

Dependencies are inferred from the claim text.

Method for imaging vessel wall anatomy and strain

Life of this patent

Method for imaging vessel wall anatomy and strain

Life of this patent

Abstract

Claims14