Back to results
US 6,143,908 AGranted
Process for preparation of 1,3-dioxolane-4-methanol compounds
AssigneeDaiso Co., Ltd.
InventorsKazumasa Hinoue, Yoshiro Furukawa
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeDaiso Co., Ltd.
InventorsKazumasa Hinoue, Yoshiro Furukawa
Estimating the term…
A process for preparing easily and economically a 1,3-dioxolane-4-methanol compound in a racemic form or an optically active form with high purity and in high yield. The process comprises reacting an alkali metal or alkaline earth metal salt of an alcohol or a carboxylic acid with a halogenomethyl-1,3-dioxolane which is prepared by acetalizing a halogeno-1,2-propanediol of a formula (1) wherein X is a halogen atom, in an acid catalyst to conduct esterification or etherification, and then hydrolyzing the ester group and hydrogenolyzing the ether group to prepare a 1,3-dioxolane-4-methanol compound of a formula (5) wherein R.sup.1 and R.sup.2 are hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R.sup.1 and R.sup.2 may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon atoms. ##STR1##
A process for preparing a 1,3-dioxolane-4-methanol compound of the formula ##STR7## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R.sup.1 and R.sup.2 may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon atoms,
A process for preparing a 1,3-dioxolane-4-methanol compound of the formula ##STR11## wherein R.sup.1 and R.sup.2 are the same or different and are a hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R.sup.1 and R.sup.2 may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon,
Dependencies are inferred from the claim text.