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US 6,143,883 AGranted
Water-soluble low molecular weight beta-glucans for modulating immunological responses in mammalian system
AssigneeMarlyn Nutraceuticals, Inc.
InventorsJoachim Lehmann, Rudolf Kunze
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Abstract
A fractionated, water-soluble, readily absorbable, low molecular weight beta-glucan is usable as an immune-modulator in the mammalian system. A method is disclosed, which produces a fractionated beta-glucan that is water-soluble and has a molecular weight between 1,000 Daltons-30,000 Daltons (1 kD-30 kD) adaptable to affect changes in the immune responses in mammalian systems.
Claims6
A method of producing a water-soluble beta-glucan, which comprises the steps of:
- (a) reacting a branched beta (1-3)-glucan with a cellulase at reaction conditions sufficient to produce a mixture of water-soluble and water-insoluble beta-glucan fractions;
- and
- (b) separating the beta-glucan mixture according to a pre-determined molecular weight for the water-soluble beta-glucan fraction.
Dependencies are inferred from the claim text.