IL-13 and IL-4 binding polypeptides
OwnerJean-Yves Bonnefoy, Jean-Fran.cedilla.ois Gauchatinventors
Life of this patent
Estimating the term…
Abstract
Polypeptides capable of binding human IL-13 and/or of binding human IL-4 in the presence of IL-4 R.alpha. can be used in medicine, in diagnosis and in screening for agonists/antagonists of IL-13/IL-4. One such polypeptide is shown in FIG. 1.
Claims8
An isolated polypeptide which is capable of binding human IL-13 and/or of binding human IL-4 in the presence of IL-4 R .alpha. or which is bound to human IL-13 and/or human IL-4;
- which:
- comprises the amino acid sequence shown in SEQ ID NO:9.
An isolated polypeptide which comprises the extracellular sequence represented by amino acids 27 to 427, shown in SEQ ID NO:9.
An isolated polypeptide which has a sequence that differs from that shown in SEQ ID NO:9 wherein the T residue number 130 and G residue number 358 shown in SEQ ID NO:9 are replaced by I and D residues, respectively.
Dependencies are inferred from the claim text.